In an area where nothing was known, medicine had to draw on social lore.

It's only when we have nothing else to hold onto that we're willing to try something very audacious and scary.

A man may be so much of everything that he is nothing of anything.

There is, indeed, nothing that so much seduces reason from vigilance, as the thought of passing life with an amiable woman.

Wine gives a man nothing... it only puts in motion what had been locked up in frost.

Nothing is more hopeless than a scheme of merriment.

Nothing flatters a man as much as the happiness of his wife; he is always proud of himself as the source of it.

Nothing will ever be attempted if all possible objections must first be overcome.

Depend upon it that if a man talks of his misfortunes there is something in them that is not disagreeable to him; for where there is nothing but pure misery there never is any recourse to the mention of it.

There is nothing which has yet been contrived by man, by which so much happiness is produced as by a good tavern.

There is no private house in which people can enjoy themselves so well as at a capital tavern... No, Sir; there is nothing which has yet been contrived by man by which so much happiness is produced as by a good tavern or inn.

There is nothing, Sir, too little for so little a creature as man. It is by studying little things that we attain the great art of having as little misery and as much happiness as possible.

So many objections may be made to everything, that nothing can overcome them but the necessity of doing something.

The happiest conversation is that of which nothing is distinctly remembered, but a general effect of pleasing impression.

Such is the state of life, that none are happy but by the anticipation of change: the change itself is nothing; when we have made it, the next wish is to change again.