The directing of a picture involves coming out of your individual loneliness and taking a controlling part in putting together a small world. A picture is made. You put a frame around it and move on. And one day you die. That is all there is to it.
A woman who is willing to be herself and pursue her own potential runs not so much the risk of loneliness, as the challenge of exposure to more interesting men - and people in general.
In the past I have never thought about loneliness when working, and I don't think about it now. Yet there must be a reason for the fact that so many people talk about it.