In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.
We must not, in trying to think about how we can make a big difference, ignore the small daily differences we can make which, over time, add up to big differences that we often cannot foresee.
The armies, the difference of all of those armies that had been fighting each other and the Taliban took advantage of that to rule over the whole country.
Today's difference between Russia and the United States is that in Russia everybody takes everybody else for a spy, and in the United States everybody takes everybody else for a criminal.
If you feel rooted in your home and family, if you're active in your community, there's nothing more empowering. The best way to make a difference in the world is to start by making a difference in your own life.
The really big difference is that what you make with a molecular machine can be completely precise, down to the tiniest degree of detail that can exist in the world.
The difference between a misfortune and a calamity is this: If Gladstone fell into the Thames, it would be a misfortune. But if someone dragged him out again, that would be a calamity.
I'm confident that, were I mayor, I would do some things differently than he has. But I think there's a world of difference between him and his immediate predecessor.
The whole difference between construction and creation is exactly this: that a thing constructed can only be loved after it is constructed; but a thing created is loved before it exists.